Home Chemistry Heterocyclic Building Blocks Pyridines Thiazolo[4,5-B]Pyridine
Alkylation: Thiazolo[4,5-b]pyridine can undergo alkylation reactions, where alkyl halides or alkylating agents are used to add alkyl groups to the nitrogen atom in the pyridine ring or other reactive sites.
Halogenation: The compound can undergo halogenation reactions, where halogens like chlorine, bromine, or iodine can be introduced into the structure.
Reduction: Reduction reactions can be carried out on thiazolo[4,5-b]pyridine using reducing agents like sodium borohydride or hydrogen in the presence of a catalyst to reduce any functional groups present in the molecule.
Oxidation: Thiazolo[4,5-b]pyridine can undergo oxidation reactions, typically using oxidizing agents like hydrogen peroxide or permanganate. This can lead to the formation of various functional groups.
Condensation: Thiazolo[4,5-b]pyridine can be used in condensation reactions to form new carbon-carbon or carbon-heteroatom bonds. For example, it can undergo reactions like the Vilsmeier-Haack reaction to introduce formyl groups.
Substitution Reactions: Substitution reactions, such as nucleophilic aromatic substitution, can occur at the pyridine ring or other reactive sites in the molecule.
Cyclization: Thiazolo[4,5-b]pyridine can participate in intramolecular cyclization reactions to form various cyclic compounds.
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2-Bromo-5-chlorothiazolo[4,5-b]pyridine
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5-Chlorothiazolo[4,5-b]pyridin-2-amine
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Thiazolo[4,5-b]pyridine-6-carboxylic acid
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